• Antimicrobial activity of amphipathic α,α-disubstituted β-amino amide derivatives against ESBL–CARBA producing multi-resistant bacteria; effect of halogenation, lipophilicity and cationic character 

      Paulsen, Marianne Hagensen; Ausbacher, Dominik; Bayer, Annette; Engqvist, Magnus; Hansen, Terkel; Haug, Tor; Anderssen, Trude; Andersen, Jeanette Hammer; Sollid, Johanna U. Ericson; Strøm, Morten B. (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-09-06)
      The rapid emergence and spread of multi-resistant bacteria have created an urgent need for new antimicrobial agents. We report here a series of amphipathic α,α-disubstituted β-amino amide derivatives with activity against 30 multi-resistant clinical isolates of Gram-positive and Gram-negative bacteria, including isolates with extended spectrum β-lactamase – carbapenemase (ESBL-CARBA) production. A ...
    • Bacterial interference with canonical NF kappa B signalling 

      Johannessen, Mona; Askarian, Fatemeh; Sangvik, Maria; Sollid, Johanna U. Ericson (Journal article; Tidsskriftartikkel; Peer reviewed, 2013-10)
    • The interaction between Staphylococcus aureus SdrD and desmoglein 1 is important for adhesion to host cells 

      Askarian, Fatemeh; Ajayi, Clement; Hanssen, Anne-Merethe; Van Sorge, Nina M.; Pettersen, Ingvild; Diep, Dzung Bao; Sollid, Johanna U. Ericson; Johannessen, Mona (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-02-29)
      <i>Staphylococcus aureus</i> is known as a frequent colonizer of the skin and mucosa. Among bacterial factors involved in colonization are adhesins such as the microbial surface components recognizing adhesive matrix molecules (MSCRAMMs). Serine aspartate repeat containing protein D (SdrD) is involved in adhesion to human squamous cells isolated from the nose. Here, we identify Desmoglein 1 ...
    • Obesity and Staphylococcus aureus Nasal Colonization among Women and Men in a General Population 

      Olsen, Karina; Danielsen, Kjersti; Wilsgaard, Tom; Sangvik, Maria; Sollid, Johanna U. Ericson; Thune, Inger; Eggen, Anne Elise; Simonsen, Gunnar Skov; Furberg, Anne-Sofie (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
      Background: Obesity and diabetes mellitus (DM) have been linked to increased risk of infections, and Staphylococcus aureus nasal colonization is a major risk factor for developing infections with the microbe. We therefore sought to find whether body mass index (BMI) and waist circumference (WC) could be associated with S. aureus colonization independent of DM. Methodology: S. aureus colonization ...